We rely heavily on drop-downs in our assets that pull values from the lists in Admin > Core > Lists, but managing these lists is a nightmare.
It's not possible to sort all list items, for example in alphabetical order, and although items can be reorganized by drag 'n drop, it doesn't allow the page to scroll which makes it a near useless feature.
Lists should be easier to manage. When dragging and dropping an item, the page should scroll when hovering the item over the top or bottom edge of the page. Also, we should be able to sort the list alphabetically or by recently added in both ascending and descending order, or alternatively, the list should automatically sort alphabetically when a new item is added.
Additionally, the ability to import a CSV to create a list would be immensely helpful.